Tuesday, April 12, 2011

Hiv Pre-Exposure Prophylaxis (PrEp)

The most basic request to ask is "What is Hiv pre-exposure prophylaxis (PrEp)?"
Pre-exposure prophylaxis is any rehabilitation you take to prevent catching a disease before you get exposure to it. So, you take this rehabilitation to prevent catching an Hiv infection, before you get exposure to the virus. This rehabilitation protocol uses antiretroviral drugs used in treating Hiv infections. The drugs that researchers are testing are tenofovir and emtricitabine in a combined tablet. Studies, done in animal models, demonstrated that this blend was very effective for preventing infection. A huuman trial performed last year also demonstrated that this blend was able to cut down on inherent infections. The midpoint allowance was 42 percent (range: 15 to 65 percent according to cases).

What is required for Hiv pre-exposure prophylaxis (PrEp) to work effectively?
One divergence between the animal and human studies is the fact that human beings are not in cages and closely monitored. The human trials involve giving the medications to high-risk groups and having them report for testing every few weeks. Test subjects who stuck with the drug protocol closely had more safety than those that did not ensue the protocol closely. So, in order for this to work, those taking the drugs must closely ensue protocols in order to get the most ensue from it. They were also advised to systematically use condoms, and these stoppage measures were assessed and repeated at each protocol visit.

Hiv

Which groups would advantage from Hiv pre-exposure prophylaxis (PrEp)?
The safest method for preventing transmission of the Hiv virus involves not having unprotected sex or not sharing used drug needles. The pre-exposure prophylaxis can be seen as an supplementary portion of prevention. Some have suggested it would work for couples who want to conceive children when one partner is Hiv obvious and the other one is not. an additional one use would be among women who have no selection on insisting their partners use condoms. Because the PrEp is not 100% effective, this should be a secondary stoppage measure.

What are coarse concerns about the use of Hiv pre-exposure prophylaxis (PrEp)?
In the Us, Aids organizations have expressed concerns that using PrEp would potentially give a false sense of safety. This might lead to lower usage of condoms among high-risk populations. an additional one concern raised is the fact that using the drug before an infection would build up drug resistance in case of infection in the future. There are ethical concerns about how the drug testing goes on among high-risk populations. These concerns comprise the use of a placebo with a deadly disease and the lack of counseling trial patients receive in some locations. The PrEp may be a step in the right direction, but it is not the excellent answer.

Finally, an additional one ethical concern is making ready antiretroviral drugs for stoppage to uninfected peopulations who can afford them, although millions of infected patients nearby the world cannot afford this therapy!

Hiv Pre-Exposure Prophylaxis (PrEp)

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