Today, science, research, and technology have done so much when it comes to addressing the problems of humankind. It has invented so many things manufacture life easier and more convenient. By just visiting a house, you can see a lot of instruments, tools, machines, and tool that aid in the plane flow of everyday life. Not only that, inventions and discoveries has helped assorted aspects of our lives. Condition and rehabilitation is one of those that benefited from science and technology. There are now drugs that can cure or preclude diseases such as heart attack, urinary tract infection, lung cancer, and many others. But there is still one pandemic that until now no one has discovered the drug that can cure it: Hiv infection.
What is Human Immunodeficiency Virus or Hiv?
Hiv
The Human Immunodeficiency Virus or Hiv is classified as a lentivirus. Hiv causes the Acquired Immunodeficiency Syndrome or Aids. It is a Condition where the immune ideas of an individual starts to fail, which leads to opportunistic infections. One may be infected with Hiv straight through the transfer of vaginal fluid, semen, breast milk, pre-ejaculate, or straight through the blood. Hiv is gift in these physical fluids as virus in infected immune cells and as a free virus particle. There are four major ways of transferring the virus and these are straight through breast milk, use of contaminated needles, transmission from mother to child, and unsafe sex.
Today, there are many researches being done to study the virus and how to reverse or preclude its consequent of failing the immune system. Many doctors and researchers are conducting experiments to find a way on how to cure this deadly virus. Currently, there are antiretroviral therapies being used to block Hiv replication. But even if these antiretroviral therapies are efficacious the infection still persists. The presuppose for the persistence of Hiv is due to the depot cells that are latently infected. This depot is carport and is established early. This is the main recognized cause of Hiv persistence.
Reservoir of latently Hiv-infected cells
The latent depot of Hiv is best characterized in memory Cd4+ T cells. There is also a possibility that the depot may exist in other cells such as the hematopoietic stem cells, macrophages, and within the brain microglia. When a sick person is treated successfully with an antiretroviral therapy for many years or even a decade, it shows that there is admittedly no critical discount in the size particularly of the latent reservoir. On the other hand, when the therapy is discontinued the relapse of viral replication is rapid.
With this kind of virus, there is a need for a life-long antiviral therapy. The problem is this kind of therapy is very prone to cumulative side effects and drug resistance. Another thing is it is a burden financially particularly in those regions where the epidemic is most prevalent.
So, the fact remains that until today there is still no cure against Hiv. The promises of antiretroviral therapies apparently do not yield all the certain results expected. So, given the fact that you still need a life-long rehabilitation an Hiv infected individual cannot expect a normal life yet. What is needed to admittedly treat the virus is to find a way on how to eradicate the depot of latently infected cells. If science and study cannot discover something to address this, then Hiv will remain a deadly virus killing thousands and thousands of population colse to the world.
What is to be done to eradicate Hiv?
Today, there is a need for a multidisciplinary and joint attempt with the goal of achieving a long term functional cure that is drug free remissions in individuals infected with Hiv. The other goal of this attempt is to found a prophylactic vaccine against the virus for those who are not yet infected.
Given the advances in technology today, a long period of investigation will still be critical to ultimately discover this cure.
Why Current Antiretroviral Therapy Cannot Cure Hiv InfectionRelated : Travel Tours Thailand
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